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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04106f148b739b8b4a170c7539ff3bff2c35f27f607695a72a54e3b65f7fe57e' 
  AND token = 'XKEYbSqMWWYwq6O9HV+T/nus4Q2pW9zN3T0gpePmgk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}