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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3661bcf956f29cbdbcd0e91c345d4d54f088cf72c1bd4f7e794346fb3fb92261' 
  AND token = 'E4srBOQd9ZxQ3XC9mZ7q+KOOXEV/YPaV9THAXU3qoxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}