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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6dfb43cb6f3cf349400f3851b1a78f51cbc563f562700de64a4c4b50b0ac783' 
  AND token = 'vdjL8vJ2PNbRaF8iqQi1YEq3jAA7W/m+qikN2cx+ZbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}