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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b52e1bfa2ef6ff0926a213cb83fe6d9760d956606961d1fa8bf810bb88f91fe2' 
  AND token = '+zYeB9Td6l2QgKvtT0PhiRAy4+1Ba4vrrTecSw43dq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}