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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f49e2445d1766a4a4aae1b5c90c7502eef09954fdf02e2fad508a2456db9e78' 
  AND token = '6cYVYvngKoBJ84ty9ecKSAoc1MZ5UJmekN3FudT5DpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}