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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '973963ce843f8865dd0f86d991640b4044fe150b8fff527448c8d09398472358' 
  AND token = 'FetBN9MT7oUNDU436+CCJrmcdlYoupk+Oj+0OGingjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}