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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d85a144e1c744b3ad76afb69fb747374d6d9321d2906568b22c53d2ffef2412' 
  AND token = 'QUOVf7nC+HpMJ9Tr0HiiVyIRg+E7Sr9WkYMTDKyN7Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}