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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2783eb139939c135a4c72b8e1add50f23fc7f4605c868dadb2666fe45064fedd' 
  AND token = 'U9cVOH2DgY/2nbBHOmgmt2CQ7NTSN6dcvHFQ99oJ1Ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}