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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38e26de6f99592efee779da1e299a9334ad16b473d79337152e99f6f72f9f9b9' 
  AND token = 'pQH8PY32RzxyIQHcgkiLcOardlsCbzlRpMS1nWxxJ/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}