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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7374454c2a24d47d6f97ff0be53691e6493fea7cd6725750ca90ba6ab8d9d01d' 
  AND token = 'dRXxV1gct+xIYHrK1+DEr5z4Mi5sgZ2EFBWkR3vsFkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}