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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c2b6b3a282581accdabcb50a0ea74f8ff88d71921643adca4e4f7a013aa0d3b' 
  AND token = 'v2b62XD0fb8m81IWcH93BfSUm6a3eZSkobZWKrlshDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}