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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '328c53baf50130e5b7715a573b7f42a55c100fe1cba1c8cdcf90912553db1b4c' 
  AND token = 'MSJH2E0ORupBjmRwSRlHeXrEC61b6GMt+q6yM8zHYv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}