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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '235b24b620fad9a016d1f2fefd3aed4e854e4667e861e79d6647927b8c23ed4a' 
  AND token = 'fzD4N7VO9yxlfo/0DIDVcZqy5qW1FTK/qBgloCyfJkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}