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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66ac6f2a5710f451df813b4c0c38539458c958eab586f7f8dc9b864e12bd006a' 
  AND token = 'D25E+xQcPqa8Z42NQmdNSULr/5q7KQgop/FJVtFKkPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}