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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1631bd4b29897cdec58213637fd0fd1979ed65e5ef18f2ee3add4c1d8d30acfc' 
  AND token = 'mk9t0TCsU+cVJ2NjI6eHVHA0A4V63H8TnFPxylHVs20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}