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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '208c58e698c04f1bd9179f70778743ea847c1ac6def3b4383ea75acf4d747d48' 
  AND token = 'vFXEXr5/yq3f18Bn3uaUJqYz/8m1D2tMPsyAK7cvEd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}