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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '252cb7e32c1947620d06963f89748170bcf75600ffa09e67d5dfb71e405f6027' 
  AND token = '+zpAVRjYRmcnMMfHxLXo8nm10LkP7/IBXxXC64+6yxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}