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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84463c88067ae2b23cc8d6af6fbf1d0d4cb4507b185f0e6dbce3b5a134cc75f9' 
  AND token = 'ICQOZ+YWogDN/+6yY8rYaRU/LYM+WxPtNH2bxV2Sv60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}