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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf2e1f896ffdba90d987138cd2ca6b6101b1ca47a9aa22eeb7c286d46bb2550d' 
  AND token = 't6t1BSpquP6D3hz5Ccd+VvwKPrBxOXakDNr66x3RyX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}