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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aab728f4554617605d6b675070a36df427a87ad92489b35a0e9280de70d10a19' 
  AND token = 'in4p4iNh3BdRsqJrp+hhanxAEUnGPNv1CAg5kuBK1UM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}