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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a395caacce0b6cc56b2016e11aa01b21d374cdf901b998b29c81a983e3efe59' 
  AND token = '0TaginsTFcH9vvOyPI1Oc3maXNLpTL6z5nDGxsSN2Cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}