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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae4feade7604fe122d02a4a849c0450d120c8cdb4e39c6a428b057413dad43ec' 
  AND token = 'mNknU2urQtpdukJaGrHGtzz15H2TOEci1JwK7d6PseY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}