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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '066ccf57177586db84cdec1352fce21b5948898f3b7bd9e0808cfdb5c3ab54c5' 
  AND token = 'UaHAnNeKTO295y1g4qVrI9P6dvE/Eqmx9gwhTCEcp5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}