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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2736c7daf1980c440d0a01749b033bf3a1c859a63c4333eaf136a15214023da9' 
  AND token = 'PF8fGdE6WbCxPAWwfTIvRWgrMRFw+G1TI0V9qoD9vnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}