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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48989a77cac8d16135dbdbcbc6beb287000c195ceca70c933b20ff0a0a80d1a9' 
  AND token = 'nTQ1+ulUu7cw9b4cG4iW/QXAT/O93n77tDwPw8+k3PM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}