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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6861899cd533faa1605781c585735a0a601448baefd8f8851e6fa5a9c04c9556' 
  AND token = 'xNHw65rPCzzGWLNJJr1l/2eQnV6rrURKtDB223zg/us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}