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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7eeb79a2743b9f56d2eee70fc85c058bb1be5f3866e25684f281aea497b5d134' 
  AND token = 'tPBjujQ+bxZNT5FbuZEUom0QQdlC93CjmgeCD2sq1XU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}