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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5017d8f4aae677a27025e9cc26757741707759a9716f6b4632f771c906621b9e' 
  AND token = 'SdL5p+Xf4LCvqzLOeM5uwWofDRd3f0NRxZXnmjwsEfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}