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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '580e06e32080af0d3f9da2b1eb3d1575e8e0e79da0e01890a3a6aaeec1b0f023' 
  AND token = 'zwV5ROZT3o1D7fUpvHc5idIT29SsIxzXQ+YVRZNU/fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}