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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c89aee1951177c722fc6862cc68539487375c5f0aa996c5b3a1c9d99425d326' 
  AND token = 'MbqDHf5qYAvM1mdoWN3jN2HdqCfJwo81fACNPzCR4sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}