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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c57dbc5fd593293e9f9bfbf017978953c07f46f4b26a41e51c520885954d694' 
  AND token = 'WuhrnmfgR88lO1YqR/QlQKWYdcCRE00XFGdOmBT/4bs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}