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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41ca1343a1ba70372b47324a747c60d0a0ef5695330122f27f7943484dfdcb2c' 
  AND token = 'Qj7Sol+vQS7WT0tBDEQEijMS6dJYTdI86MLN9Yn/m4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}