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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64c507cdfd8e3daeb1e97a4b3599861d17eecd87ff10b73e337e8619a07da465' 
  AND token = '4BGT2qJE0xLHYHNT7YPTZX6kTOUV2pjJWhdHzkL8rtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}