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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afb248074374d56a5bae5c216cf0708c9643837d1cc67b3102fd1a22a02873ef' 
  AND token = 'LxzWvYEZgW+m198W4PGukUzAyhSy6Fv620pFhcaM6vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}