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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e7409e9e09702ecbf6e8af4de2a7d58140ebb35ff00b42273c01a712deb7c62' 
  AND token = 'HDsepxGuTzw5nLxz+QKcXVHi7NTxO7Wr+KMH2I8zzyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}