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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e18fb45645d5db31023fbda7d39edf8f270364909aa0477ebddbefff6b73b2f7' 
  AND token = '2Ozs9y1tFjuhfI1DujR5t7vpLXPOWf39ebQuo3BCuzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}