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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b251f88f8c008cae9bfa4c5a9fe0f4c26ec50b387414507eee760fae015b3a7' 
  AND token = 'YhWBN7Msrya6boGGgqvTt7Ejch5VQSBtyFlyW+nZNa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}