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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb3a48d90d4163bf57dc9a09f570ce0580443f6979cd2c6073732d8d5e4d7e21' 
  AND token = 'I9ToD2eupYTjuckpdg5REXFlr+0OkOMLsKyIwK97KxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}