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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456f18ffee8eb472dca16f6e9aa1ff5d5c8dd0d360586ac2a98b2a58a2ef1977' 
  AND token = '68wy5nyUeBC+mpx0CgnkKR8iQ+t57B2giu0vI8+X2/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}