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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3337cf679c4a7c649ec5bfdb152190120ca8abdf5b7171306d14f6f3b818f2d' 
  AND token = '8EBFp25onJ+4YNB2QiwADBMxcZLnLd4nkrp+U2tbrsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}