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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ec4e8a454250a8118702936d05e0c7e3a0e15c13bdbe68471739a344fcc556' 
  AND token = 'TGeboq48A5Mn6yeQF1aOm9l5NSW97C+R1QAbIMKvT+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}