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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a65cd4acded6dcaa181929ef03e066c3ac51cbd8c08407f826068e6cc8939e6' 
  AND token = 'I5FDwXT2txM2X86280HKIY6VLVpBiqcmH60pagRLB6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}