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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '96ee374051f76974a11cab8761638594271d38ed3643ee7c798ac2de61228f9f' 
  AND token = 'TYWX63J2bfJhgwXL6rTAfj+t24NF7OSyDI7GtQi6OdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}