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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b100f3f082c1d25a66d9340d9611ad1c5a29455a3b234fde1389147d8e2ea58' 
  AND token = 'KXn3VofBmXiMstNC1AMYz8FWdpq724/QEKA8TNbX7G0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}