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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06820570819c44740a70d289a0460d4b2200941a93953efa85f6c4d2a58708ee' 
  AND token = 'cKffryNdVHCg+jho/m5K9ir+5AQ1JYhCuIsEHmSTNx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}