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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74010d87206855aded6d790986794f1d91c0cc9dc2776ad0a475ebd2f5b72d99' 
  AND token = '4SDFSplA58gn2AUEtOY+jozP7CzvakBlNQHp7UT1dF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}