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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d1f6230d648c93beacea4a8f88d7682d856dbbd3f8585a85d158554c1b57a78' 
  AND token = 'BIW0+f+3uS5Yw3C7upjvbDwhXDkCTO0cgp0d2g/RKA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}