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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa1fc66821a78e651eb19a8d98cdd9af1f21a94222f885d8818563f19e150e04' 
  AND token = '+Y3RFdjExb2SLckUOedtpb39++hrOT5C9qIAMWv7HcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}