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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c2b865bb3b780981c44d564cae6913c3d9014cc8471c93fa0ff947406949ee5' 
  AND token = 'qYCz+Zfg4Faj5Y6iDq8M8K0PFeR4/FjpXCALgql3jDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}