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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea92c0064055b7f65cd36fb060fa743f139e9551a284a83858dc06e59b3c3d9b' 
  AND token = 'VtipD/u6SPfNcdhGfgtRB161hpRzVaDOc5Xe1q/ZDp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}